Long-term effects of frequent anesthesia?

Over the past 28 years, I've had 12 surgeries (cosmetic and reconstructive), 6 times under general anesthesia and 6 times with IV sedation. I am considering another cosmetic procedure that would require general anesthesia (about 90 minutes long). Are there any known major negative effects from having so much anesthesia over all these years? Thank you.

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