Best Treatment for Dermatosis Papulosa Nigra (DPN)?

I have problem of dermatosis papulosa nigra (DPN). Is there any liquid medicine to apply on it to remove it. Also is there is any medicine to take inside. I heard there is effective medicine in homeopathy.

Doctor Answers 7

DPN Removal

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Hello Mr. P.  Removal of DPN, or Dermatosis Papulosa Nigra is quite simple with a low level electrical probe called a hyfrecator.  This process is commonly referred to as cauterization and it involves using heat developed by the electrical probe to remove the lesion.  Typically a small scab develops after treatment and this falls of within a week.  

When done well, the skin should look clean with no scarring.  To see a good example of before and after photos for the type of procedure we are referencing, click on the link below.

Los Angeles Facial Plastic Surgeon
4.4 out of 5 stars 7 reviews


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Most physicians prefer electro-dessication for treating dermatosis papulsa nigra. This is simple, safe effective,  and if done properly, should not leave a scar. Cryotherapy can also be used but there is a risk of post-inflammatory hyper-pigmentation. Laser, for those with money to burn, can also be used. It creates a scab which will fall off a few days later.

I realize there are some liquids and creams advertised on the internet, but I would rather not dignify them as an alternative ( not so much for this use. but for the fact they also claim to take off moles....presenting a huge risk to the public, just so they can make a buck).

An oral medication to relieve yourself of dermatosis papulosa nigra, I can assure you, is a scam.

Arnold R. Oppenheim, MD
Virginia Beach Dermatologist

The Iridex 532nm laser

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I have published a paper on this treatment. It is remarkably safe and effective, even on the darkest skin. It is a 532 nm laser with a very small 1mm or less spot size for precise delivery of the energy. There is a great risk of pigment disruption with any other treatment. I have pictures of results on my web site.

Mary P. Lupo, MD
New Orleans Dermatologist
5.0 out of 5 stars 18 reviews

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Dermatosis papulosa nigra (DPN) treament

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Removal of dermatosis papulosa nigra (DPN) lesions is generally simple, fast and effective.  If the lesions are flat, they can be removed with light electrodessication and gauze abrasion.  Raised lesions may need to be snipped off.  Numbing cream can be applied in advance to make the procedure more comfortable.  Antibiotic ointment is applied immediately afterward and twice daily for the following week until the treated areas heal.  Patients often find this procedure very satisfying as they see results immediately, it is fast, relatively low risk and generally affordable.  Even if every lesion is not removed, patients report notcing that their complexion appears clearer and fresher.

Dina D. Strachan, MD
New York Dermatologist

DPN's are usually pretty easy to treat with either light electrodessication or focal erbium laser

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Simple electrodessication can be very effective for DPN's, but use of low settings is very important. Patients should avoid picking or manipulating these areas, as this can increase the risk of discoloration that is persistent. Snip-removal can also be helpful for larger, more pedunculated lesions. For larger areas, an erbium laser can be very helpful, reliable and effective and avoids the use of liquid nitrogen (which is more likely to lead to discoloration or scarring).

Joel L. Cohen, MD
Greenwood Village Dermatologic Surgeon

Dermatosa papulosa nigra

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I am not aware of any cream or liquid that can safely eliminate these lesions without creating a hyperpigmentation concern. These benign growths, dermatosa papulosa nigra are usually treated by snip excision, cauterization or other treatments but there can be a discoloration, lighter or darker, usually temporary. The risk of scarring exists.

Ronald Shelton, MD
Manhattan Dermatologic Surgeon
4.9 out of 5 stars 39 reviews


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lots of ways to treat- KTP laser with small spot or electrosurgery both work well- would not endorse any topical cream etc

E. Victor Ross, MD
San Diego Dermatologic Surgeon
5.0 out of 5 stars 4 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.