Tretinion can cause your skin to look dramatically worse for the first 1-2 months after starting treatment. Redness, flaking, burning, and breakouts are common in this period. This is the time that most people "give up" and stop using the cream. Your skin should begin to stabilize and improve in the next few weeks. It is important to still visit your prescribing physician for routine monitoring and to make sure you are using your prescription appropriately. Hope this helps.
Johnson C. Lee MDPlastic Surgery