Lip Injections for Preventing Cold Sores?

I get cold sores every winter. I'm wondering, if I were to get any type of lip injections, can that keep me from ever getting cold sores again?

Doctor Answers 6

Absolutely not

In fact treatments like laser, exfoliation (think dermabrasion or microderm) and peels can trigger cold sore outbreaks. Most plastic surgeons will actually pre-treat with medications to suppress outbreaks for some of these more aggressive treatments (but typically not for injectables).

I hope this helps.

San Francisco Plastic Surgeon
4.8 out of 5 stars 49 reviews

Injections will not prevent cold sores


This is an interesting question, but there is no correlation with lip injections and reduction of cold sores.

David Shafer, MD
New York City

David Shafer, MD
New York Plastic Surgeon
4.9 out of 5 stars 75 reviews

Probably not

Cold sores can come as a result of trauma (from injections) or from stress, or just because the viruses camping out on the nerve endings feel like causing trouble.

Patients who are prone to getting cold sores may wish to obtain a prescription for antiviral medication from their doctor prior to injection.

There are to my knowledge no injectables that prevent cold sores, only that predispose to their formation.

Brent Moelleken, MD
Beverly Hills Plastic Surgeon
4.9 out of 5 stars 177 reviews

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Although I have never seen an injection spur a cold sore, it can happen with the stronger peels.This is the reasoning behind anti-viral prophylaxis with these deeper peels.


Best Regards,


John Di Saia MD


John P. Di Saia, MD
Orange Plastic Surgeon
5.0 out of 5 stars 27 reviews

Definitely not!

There are no medications which can be injected into the lips which can prevent cold sores to my knowledge.

What is very important to recognize is that injections into the lips can very well induce an outbreak of cold sores from the localized trauma to the area if you have developed cold sores in the past! If you have a history of developing cold sores and are planning on any type of localized injections into the lip region, definitely be sure to let your plastic surgeon know before hand, and you may want to pretreat with Valtrex, which is a prescription that can be provided to you by your physician.

By the way - the same goes for any resurfacing procedure (such as laser, chemical peels, dermabrasion) to the mouth or lip area!

Brian S. Glatt, MD, FACS
Morristown Plastic Surgeon
5.0 out of 5 stars 48 reviews

Lip injections and cold sores

Actually just the opposite.  Lip injections can cause an outbreak of cold sores whcih are basically herpetic lesions.

Steven Wallach, MD
New York Plastic Surgeon
4.1 out of 5 stars 29 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.