Do topical peptides have any long term benefit?

Doctor Answers 5

Long term benefits from peptides?

I don't believe there are any long term studies. Probably mainly 3-6 months is the longest. Retin A is the best long term treatment for skin and there are extensive studies over years regarding its benefits. Results from RF, lasers, and chemical peels will be more noticeable and better than peptides IMO.


Panama City Facial Plastic Surgeon
4.8 out of 5 stars 45 reviews

Long term benefits from peptides?

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I don't believe there are any long term studies. Probably mainly 3-6 months is the longest. Retin A is the best long term treatment for skin and there are extensive studies over years regarding its benefits. Results from RF, lasers, and chemical peels will be more noticeable and better than peptides IMO.


Panama City Facial Plastic Surgeon
4.8 out of 5 stars 45 reviews

The Key to Facial Rejuvenation

You can still get better and longer lasting facial rejuvenation with lasers or RF, sculptra for collagen building, microneedling/prp and in addition to skin care. I suggest speaking to a board certified dermatologist or plastic surgeon about the results you want.  Best, Dr. Emer.

Jason Emer, MD
Los Angeles Dermatologic Surgeon
4.8 out of 5 stars 203 reviews

The Key to Facial Rejuvenation

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You can still get better and longer lasting facial rejuvenation with lasers or RF, sculptra for collagen building, microneedling/prp and in addition to skin care. I suggest speaking to a board certified dermatologist or plastic surgeon about the results you want.  Best, Dr. Emer.

Jason Emer, MD
Los Angeles Dermatologic Surgeon
4.8 out of 5 stars 203 reviews

Do topical peptides have any long-term benefit?

Thank you for sharing your question.  Because of the lack of evidence for peptide use I would advise spending your money on more proven therapies such as Retin-A, Botox, and dermal fillers. Hope this helps. 

Do topical peptides have any long-term benefit?

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}

Thank you for sharing your question.  Because of the lack of evidence for peptide use I would advise spending your money on more proven therapies such as Retin-A, Botox, and dermal fillers. Hope this helps. 

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Peptide treatment

I am a believer in topical peptides as a tool to help rejuvenate skin, especially- in addition to retin-A or retinols which have proven long term benefit.  I do believe they have a role in addition to other skin treatments.  

Peptide treatment

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I am a believer in topical peptides as a tool to help rejuvenate skin, especially- in addition to retin-A or retinols which have proven long term benefit.  I do believe they have a role in addition to other skin treatments.  

Topical Skin Rejuvenation

Dear camcon:

Properly formulated topicals can be very effective in remodeling the skin and preventing sun damage. But for every effective formulation there are probably 10,000 that do nothing more than temporarily moisturizer the skin. Agents with a large body of scientific data include retinoids, glycolic acid, vitamin C, growth factors, green tea polyphenols, caffeine, coffee berry, and Alastin.  Often, concentration and pH can be critical to efficacy.  It is best to ask your dermatologist as most of us have devoted ourselves to researching the best formulations.

   All the best,   Dr. Clark 

Topical Skin Rejuvenation

{{ voteCount >= 0 ? '+' + (voteCount + 1) : (voteCount + 1) }}

Dear camcon:

Properly formulated topicals can be very effective in remodeling the skin and preventing sun damage. But for every effective formulation there are probably 10,000 that do nothing more than temporarily moisturizer the skin. Agents with a large body of scientific data include retinoids, glycolic acid, vitamin C, growth factors, green tea polyphenols, caffeine, coffee berry, and Alastin.  Often, concentration and pH can be critical to efficacy.  It is best to ask your dermatologist as most of us have devoted ourselves to researching the best formulations.

   All the best,   Dr. Clark 

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.