Prevelle Risks or Side Effects

What are the risks of side effects of Prevelle Silk and Prevelle? What should I know before getting the treatments?

Doctor Answers 3

Not Very Risky

Prevelle would generally have the same risks as the other hyaluronic fillers. As I see it the main risk is tissue necrosis if the filler impinges on a blood vessel. There would beb a slight additinal risk of an allergic reaction to the xylocaine that is used as an anesthetic in the syringe. However, this risk is very small.

In some ways Prevelle woudl be a little less risky than the other hyaluronic filler since it does not last as long.


Virginia Beach Dermatologist
4.5 out of 5 stars 13 reviews

Low risk

Prevelle Silk is an FDA approved dermal filler uniquely formulated to temporarily decrease the evidence of fine wrinkles and deep tear troughs. The filler is composed of hyaluronic acid, which is naturally occurring in the body and resorbed over time. Prevelle Silk differs from other fillers in that it does not swell over time and can be injected very superficially, which is perfect for tear troughs and fine lines around the mouth and eyes.

Prevelle Silk treatments are only available through healthcare professionals who are trained and experienced in dermal filler injections. The treatments are given in an office setting, where a very fine needle is guided below the epidermis and into the connective tissues within the dermal area of the face where deep lines and folds develop. There, the filler works like a sponge within the skin, where it also absorbs water, giving you a more youthful appearance.

Prevelle Silk contains a pain-numbing lidocaine anesthetic, which keeps patient discomfort at a minimum. In most cases, Prevelle Silk treatments are performed in just minutes and require little or no down time, although bruising may occur no matter how experienced the injector. Cosmetic results are instantaneous, and the younger appearance achieved in a single Prevelle Silk treatment can last up to 4 months, after which time the body safely absorbs the biocompatible filler.

The rule with filler injections is... if it feels like a lump and looks like a lump, massage it down. If it doesn't go down with massage, it can be reversed with hyaluronidase injections. If it is a lump occuring months after the filler was injected, it could be a granuloma. Granulomas occur rarely and the treatment is steroid injection. Either way, you should speak to your practitioner about your concerns.
My best,
Sheila Nazarian

Sheila S. Nazarian, MD
Beverly Hills Plastic Surgeon
5.0 out of 5 stars 39 reviews

Risk with Prevelle

The risk is very, very low.  Prevelle is really smooth so lumpiness is rare.  The risk of injecting a small artery and causing a loss of skin is really, really low.  If the Prevellle is injected in the wrong area or too much is used it will be gone by three months. For almost immediate reversal of the Prevelle, the area can be injected with hyaluronidase which will dissolve it overnight.

The risk of any filler is very dependent upon the person injecting it.  It is important to seek out a physician who is very familiar with the underlying anatomy, a surgeon for example! 

Lisa Lynn Sowder, M.D.

Lisa Lynn Sowder, MD
Seattle Plastic Surgeon
5.0 out of 5 stars 60 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.