These type of deep scars are very difficult to treat and need a combination of lasers such as eMatrix and Fraxel and dermal fillers to improve the appearance. Please consult a dermatologist who specializes in these scars.
Best treatment for acne holes
There is no single best treatment for the deep acne holes/scars seen in the photo you provided. Certainly, deep scars require deep facial resurfacing methods which can be accomplished with deep chemical peels or continuous, nonfractional lasers. Dermal fillers and punch excisions and subcisions are excellent adjunctive treatment for this condition.