Yes, it can often be improved, but the best treatment depends on what is creating the fullness around the mouth. If this is caused by sagging lower-face tissues and early jowling, a facelift can reposition the tissues and improve the area around the corners of the mouth and jawline. Simply adding filler may not be the best solution, especially if there is already excess or heavy tissue in this area. If there is also volume loss around the mouth or cheeks, carefully planned fat grafting or filler can sometimes be added after the lifting procedure. I would recommend having the area assessed as part of the entire lower face rather than treating the “bag” as an isolated problem. Often, correcting the underlying tissue descent gives a much more natural improvement than simply filling the area. A consultation with an experienced facial plastic surgeon would help determine whether you would benefit more from a facelift, a more limited lift, or a combination approach.