I had collagen injected into my lips and had a severe reaction. Is it safe for me to try Juvederm?

Collagen is the main structural protein found in our bodies, and can be derived from a human or animal source (typically pig or bovine) for cosmetic use. Collagen fillers are largely a thing of the past, due to the higher probability of allergic reactions, and unpredictable longevity.
Having an allergic reaction to collagen fillers should not rule out treatment with Juvederm.  Juvederm, as well as the majority of fillers currently on the market, are made of a synthetic version of hyaluronic acid, a naturally occurring molecule found in the human body. Unlike collagen fillers, allergy tests prior to treatment are unnecessary, due to the very, very low probability of an allergic reaction.

If you would like to be extra cautious, you may first have a “test spot” injected in an inconspicuous area, and monitor the area for any reactions in the following days. You will likely find no change, and may move forward with treatment shortly thereafter. Be sure to first consult with a board certified Dermatologist. Best of luck. 

Juvederm is comprised of hyaluronic acid and therefore it is very unlikely that you will also be allergic to juvederm even with your history of allergy to collagen injections. If you are still concerned, you can have a small test spot injected into a less conspicuous area such as behind the ear to see how your body reacts. FInally, with all hylauronic acid fillers significant swelling, bruising, and tenderness can occasionally occur after injection and it is more of a reaction to the needle penetration rather than the filler itself. Hope this helps!Johnson C. Lee, MD Plastic Surgery