The Juvéderm Collection is one of the most well-known lines of FDA-approved injectable fillers. Manufactured by Allergan, Juvéderm fillers are made with hyaluronic acid (HA), a molecule found naturally in the skin that has a unique capacity to attract and retain moisture: it can hold up to 1,000 times its weight in water, which helps skin look plump, supple, and youthful.
Injected beneath the skin, these gel-like fillers instantly help smooth fine lines and wrinkles, soften creases, enhance contours, and restore volume. Clinical studies also suggest that HA dermal fillers may stimulate the body’s natural collagen production in areas of the face where it’s injected, improving skin firmness and elasticity.
“Since hyaluronic acid is found naturally in the skin, the body accepts it, and the filler persists until it’s slowly absorbed over time,” says Chicago-based facial plastic surgeon Dr. Anil Shah.
All Juvéderm fillers contain cross-linked hyaluronic acid, meaning that the molecule chains are connected. The HA gel remains clumped together, slowing the rate of absorption and providing longer-lasting results.
Each HA formula in the Juvéderm collection of fillers has its own properties, longevity, and intended treatment areas.
Cheek, chin, and jawline fillers
- Juvéderm Voluma XC contours the face by adding projection to the chin and definition to the upper arch of the cheekbone.
- Juvéderm Volux XC is the only FDA-approved HA filler for defining and sculpting the jawline.
Lip fillers
- Juvéderm Ultra XC plumps lips.
- Juvéderm Volbella XC creates subtly fuller lips and smooths vertical lip lines.
For lines and wrinkles
- Juvéderm XC smooths parentheses lines around your nose and mouth (nasolabial folds).
- Juvéderm Vollure XC (known as Volift in Europe) softens lines around your nose and mouth.
- Juvéderm Ultra Plus XC smooths moderate to severe facial wrinkles, particularly around the nose and mouth.
For under-eye hollows
- Juvéderm Volbella XC is the first dermal filler to be FDA-approved to fill in tear troughs and reduce the appearance of dark circles.
For hydration and skin quality
- Juvéderm SkinVive (known as Volite abroad) was recently FDA approved to improve skin smoothness of the cheeks. As the first “skin booster” on the U.S. market, it’s made to be injected into the dermis, below the skin’s surface, in microdroplets that hydrate and plump skin from within. According to a company press release, a clinical study found that six months after treatment, 63% of patients were satisfied with how radiant their facial skin looked, 72% were satisfied with how hydrated it looked, and 83% were satisfied with how healthy it looked.
An experienced injector can choose the right fillers to create the most natural-looking result.
RealSelf Tip: Hyaluronic acid fillers have long been used off label in the tear troughs, to fill in under-eye hollows. While Juvéderm Volbella XC was recently FDA-approved for use under the eyes, some injectors think it’s ill-suited for the area, due to its propensity to swell and its strong crosslinking, which makes it long-lasting and difficult to dissolve should problems arise.
Doctors on RealSelf don’t recommend using Juvéderm Ultra or Ultra Plus under the eyes either, due to the likelihood of a lumpy appearance under the fragile, thin skin in that area. “Ultra and Ultra Plus hold onto water, which can make them swell and create a blue discoloration in this thin-skinned area,” cautions Dr. Lorrie Klein, a dermatologist in Laguna Niguel, California.
For these reasons, many injectors prefer thinner, less absorbent fillers like Belotero Balance, Restylane Eyelight, RHA 2, or Revanesse Versa for the delicate under eye area.
