Is Asclera (polidoconal) a Safer Sclerosant Than Sodium Tetradecyl Sulfate?

There is evidence that the risk profile of Asclera is less than that of STS, but both solutions are safely used to eliminate unwanted spider veins.  Choosing the appropriate sized veins to treat, and patient selection are important in reducing complications and improving results. 

I have been using polidocanol for more than eight years.  I have not had not even one case of adverse reaction in over a 1000 of patients that I have treated.  This product is safe and effective.  The average cost is aout $400 to treat the spider veins.

Thank you for your question.
We routinely use both Asclera and STS in treatment of spider and varicose veins.  If a severe allergic reaction is reported to one, we do not use the other. While I prefer Asclera over STS (for less pigmentation changes), I would not recommend  its use if you had an anaphylactic reaction to STS. 
I would consider hypertonic saline or if your veins a small and isolated, laser treatment. 
I hope this helps.  

Best,
David Singh, MD