No need for a "low mood" We are all the products of our genetics (and it may be something inherited from a grandparent or even great-grandparent we never knew). The issues here relate to volume deficit, which can be quite easily addressed with the use of HA fillers.. First, the upper cheeks acts as a support for the under-eyes and also pull up on the smile line (and to some extent on the marionette lines, as well). So, by restoring volume to the upper outer cheeks with a robust HA filler, we can soften the tear troughs, diminish the smile lines and improve a bit the marionette lines around the mouth. A robust HA filler can straighten an define the jawline and eliminate the jowls. And, it can be used to straighten the angles of the mouth. In experienced, all of the foregoing can be done in one 30-45 minute treatment session. So, don't despair. Instead, you would be wise to consult a board certified cosmetic dermatologist and best of luck.