Great question and good for you for being proactive in the decision making process. The simple answer is, yes, in general it is possible to undergo autologous or own tissue breast reconstruction after initial placement and fill of a tissue expander implant. In fact, most breast reconstruction surgeons, when planning own tissue breast reconstruction, prefer to complete the tissue transfer part of the reconstruction after the radiation. That's so the newly reconstructed tissue is not subjected to radiation injury. However, there are many considerations that go in to determining what type of own tissue reconstruction you're a candidate for or even whether your a good candidate at all. That can only be decided upon by an individualized evaluation of your case by a breast reconstruction surgeon with experience in all types of tissue transfer procedures. Stay curious and expectant of only the best for yourself. Take care.