Permanent solution for wrinkles and lines around mouth?

I would recommend some type of resurfacing procedure such as C02 laser. It is very safe and is considered the gold standard for improving wrinkles. Fat grafting may help significantly since often wrinkles are a result of volume loss as well. If your prefer to use other injectables, I would recommend any number of the hyaluronic acid products currently available.

Fractional laser is an amazing and highly effective treatment in our office. We use the laser treatment to help with acne scars, large pores, fine wrinkles, tissue collagen loss, scars, sebaceous hyperplasia, active acne, and for brightening dark pigmentation. Although there are very strong fractional lasers such as CO2 laser, we use lighter treatments for corrective skincare and maintenance of results. Our Thulium fractional laser, clear and brilliant laser, and Ultra Thulium laser are excellent options in our clinic. We also perform CO2 fractional and erbium depending on skin tone and tolerance for downtime. Patients do have to use a Melarase cream before and after treatment to help further reduce pigmentation after laser. Melarase AM, Melarase PM, and Melapads can seriously improve surface sun damage and UV related pigmentation. Dark spots can improve with these treatments. I recommend fractional laser for incisional scars as well, especially after plastic surgery.
Best,
Dr. Karamanoukian
Realself100 Surgeon

Facial aging happens because of 3 main reasons.
1. We lose fat as we age over time.
2. Skin loses elasticity.
3. Bone is absorbed over time.
Surgical decisions are made based on anatomy, age, skin type and bone structure to start.  I would recommend facial fat transfer and superficial laser or radio-frequency depending on how much downtime you can work with. For the jowls we need to tighten the skin and muscle. For the neck we need to tighten the platysma and do a submentoplasty (under the chin incision).  The best thing to do is find a surgeon you trust and go over your goals slowly and clearly.
Hope this helps.
Best of luck,
DrC

Marionette lines, or smile lines, can be very difficult to treat.  They result from the underlying muscle that controls lip movements.  A facelift will not address these lines.  Dermabrasion is difficult to treat these lines as well unless it is of sufficient depth.  In my practice, for moderate to severe smile lines, the Erbium laser works well.  This is an ablative laser which means it removes the outer layers of your skin using controlled heat.  This not only softens these wrinkles but also aids in collagen production which provides a more youthful appearance.  People with lighter skin tones are better candidates for this laser as darker pigmented individuals are more prone to developing hyperpigmentation.  It is very important to consult with a board certified plastic surgery with extensive experience and expertise in laser surgery.

Wrinkles around the mouth are called Marionnette lines (lateral to oral commissure) and Vertical Rhytids around the central lip areas. These are very difficult areas to fix as a Facelift only pulls this aea laterally and the dissection does not and cannot extend into the lip area. 
Every Facelift I perform gets a Dermabrasion treatment that involves diamond burr sanding of the peri-oral area to the interface between deep and superficial dermis to stimulate new collagen production. This remains the Gold Standard for treatment of these lines but may need to be repeated 2-3 times. It is not possible to completely get rid of the lines and any treatment that promises this is not true.

The wrinkles are permanent breaks in the skin, and very difficult to treat. As a matter of fact they can never be corrected totaly however there are various measures to make them look better. Resurfacing is a must. Dermabrasion and CO2 lasers can help with that. I prefer dermabrasion. However, sometimes you need to reduce the activity of the muscles underlying and fill the subcutaneous pocket with some tissue. Fat grafting and fillers will help. Botox is a must to reduce the hyperkinetic activity of the muscles.
Hope this helps,
Ali Rıza Öreroğlu, MD FEBOPRASEuropean and Turkish Board Certified Aesthetic, Plastic and Reconstructive SurgeonIstanbul, Turkey