What is best for the wrinkles under my eyes when smiling? (photos)

Thank you for sharing your question. Based on your photos, you are an excellent candidate for injections with a neuromodulator such as Botox, Dysoprt, or Xeomin. In particular, a small amount of Botox to the lines under the eyes will soften the appearance of the wrinkles you are noticing. I also recommend a small amount of tear trough filler with a hyaluronic acid filler such as Restylane. This will restore lost volume in the area, which will make you appear less tired. I prefer to inject filler into this area using the microcannula technique, which is essentially bruise-less and minimizes the risk of swelling in the area. I recommend scheduling a consultation with a board-certified specialist who is experienced using the microcannula technique for injecting fillers. 

I have been using Botox for well over twenty-five years and for under the eye crinkles, wrinkles and so-called "jelly rolls" for almost as long. A tiny microdroplet of Botox injected directly into the body of the area in the mid-pupillary line is quick, almost painless, not expensive and may prove quite helpful and certainly worth a try, in my estimation. Although the photos are not ideal, there is a strong suggestion of volume loss in both the cheekbone region and in the cheek region immediately below the eyes. I believe that appropriate use of a volumzing filler to the cheeks, followed by the use a filler for the immediate infraorbital area will go a long way to providing overall facial and under eye improvement, particularly if coupled with the Botox. The under eye region should not be left to novice injectors accustomed to injecting only Botox in eleven lines and simple fillers like plain Juvederm or Restylane into smile lines. You would do well to consult with a board certified aesthetic physician with experience and expertise in the nonsurgical treatment of under eye problems and make sure to ask to see his/her before and after photos before agreeing to proceed. Good luck to you.  

A combination approach would give the most improvement. I recommend lasers, microneedling/prp and fillers. See a cosmetic dermatologist for a formal evaluation. Best, Dr. Emer