I’ve tried multiple brands and types of lip filler and none last past 4 months. Can I stop my body from metabolizing it?

Thank you for your question.  May I ask which fillers did you use? There are different dermal fillers that last anywhere from 6-18 months in lips. 

I do not know what brands or fillers you have tried, but I find it very unusual that you have found none that last very long, as there are now multiple ones that usually last up to a year and a few that will last about 18 months. It also depends on the injection technique, some lasting longer than others. If you have, indeed tries them "all," then there is always fat grafting. Some physicians do not like fat because "it doesn't last." This is simply because they do not understand how to do the injection of it. What you need to do is gather information about everything you have had injected and see an expert plastic surgeon who is experienced with both fillers and fat.