Thank you for your question regarding what to do with an opening of an incision at the top of your buttock crack three weeks after a lower body lift. Wound breakdown is one of the most common complications after a lower body lift. The top of the buttock crack is notorious for break down. The BEST treatment for this area is wet to dry dressings. Various solutions can be applied during the wet to dry dressings, ranging from normal saline to Dakin's. These will debris the wound and accelerate healing. Once the collagen and yellow tissue is debrided, you can move on to topical creams to expedite the healing. However, at this time, the best treatment for this area is wet to dry dressings. Thank you for your question regarding what to do with wound breakdown at the top of the buttock crack after a lower body lift. I specialize in reconstructive plastic surgery after weight loss. If you have any more questions regarding the lower body lift, 360 circumferential lower body lift, belt lipectomy, belt abdominoplasty, or belt dermolipectomy please contact my office. Since the body lift is a big procedure, please seek an experienced, board certified plastic surgeon with significant experience performing the lower body lift. Do your research. Make sure they have performed at least 100 circumferential lower body lift surgeries and have the before and after pictures to prove it. Carefully examine their before and after pictures and check their reviews on RealSelf. If you cannot find an experienced, lower body lift surgeon in your neighborhood, consider traveling out of state if you must. Sincerely, Dr. Katzen. (“Verified” Plastic Surgeon, President of the American Society of Bariatric Plastic Surgeons, certified by the American Board of Plastic Surgery, Fellow of the International Society of Aesthetic Plastic Surgery, American College of Surgery, and International College of Surgery and member of the American Society of Plastic Surgery, American Academy of Cosmetic Surgery and RealSelf Hall of Fame.)