I am 2 was PO for TT and my PS had to clean an area on my incision because he didn't like the way it looked. It's now a very small hole. I would say about the size of a pencil eraser. I was told to apply twice a day in the wound only. Avoiding the surrounding healthy skin. I Googled Santyl and saw some horrifying reviews. I have to say that wound care was in the top 5 of my list of very scary repurcussions of this surgery. Somebody please give me some good news.