My mouth droops on one side. I was thinking about asking for Refyne or Defyne? Which one? (photo)

Thank you for sharing your question and posting your photo. Fillers will not be sufficient to treat your problem. NovaThread lifting would be more appropriate. See an experienced Oculofacial Surgeon for in person comprehensive evaluation and proper guidance. Good luck,

Hello Donna.In my office you would receive a combination of fillers. I would start out with Restylane Lyft first and reverse the tendency to droop by adding volume to your cheeks. I would also consider Defyne for the deeper folds and refine for the finer folds. Next, I would use Dysport or Botox to relax the muscles pulling the corners of your mouth down. Finally, I you need skin care including chemical peels, daily therapy at home, and microneedling/dermaplaning.Best wishes, Dr. ALDO 

Since I do not have an entire picture of your face, it is difficult to an adequate assessment of your face. Sagging of the corners of your mouth usually involves loss of volume from the cheeks as well. I would start by replacing volume in the cheeks, using Restylane lyft which can be used deeper and gives great support. Then after that, I would use Restylane Lyft at the corners of your mouth as well. When evaluating the face, I always like to do a global assessment.