Hi Exciting721726, Factor VIII activity plays an essential role in blood clotting, and elevated levels can influence the risk of thrombosis or blood clot formation. If your factor VIII activity level is 159, it's indeed higher than the standard range you mentioned. Elevated factor VIII levels can increase the risk of blood clots. While liposuction itself can also pose a risk for blood clots in the legs (deep vein thrombosis), having an elevated factor VIII level could compound that risk. Before considering liposuction or any other surgical procedure, it's crucial to discuss your medical history and any lab results with both your hematologist and your plastic surgeon. They'll be able to assess your overall risk and guide you on the best course of action. They might recommend specific precautions or even suggest alternative treatments that might be safer for you. Your safety and well-being are paramount. So, while liposuction may provide excellent cosmetic results, it's essential to ensure that it's safe for you to proceed, given your unique medical background. Thank you for your question. Please consult closely with your medical professionals, and I wish you the best of luck in your journey. Sincerely, Dr. Katzen