I have RA and I'm on medications for that will it affect me having breasts enlargement? Methotrexate 2.5 mg take 4 once a week

Methotrexate can affect your ability to fight infection so potentially it may increase that risk post op but as long as your surgeon knows ahead of time proper steps can be taken to mitigate this risk. On the other hand, it decreases inflammation so it may theoretically lower your risk of capsular contracture down the road (I am unaware of any evidence to support this though). For a more thorough answer get a consultation with a board certified plastic surgeon near you and discuss this in more depth. Best of luck.

I understand your concern. Your best option is to have your plastic surgeon consult with your rheumatologist to develop the best options for your surgery. You may be able to stop the medication for a short period before and after surgery, but ultimately your doctors should get together and review all options.

You should ask your rheumatologist about elective surgery while on this medication. You may be at a higher risk for infection or healing problems but it should still be generally safe.