Are Breast Implants Hypoallergenic?

There is probably no medical device that has been studied more intensively in terms of the potential to stimulate an immune response than breast implants. (Allergy is an immune system response.) Since both saline and silicone gel implants have a silicone shell, the question is a very important one. A few years ago, there were a couple of reports in the medical literature of allergy-type reactions to implants, but it relates more to impurities and not the silicone itself, and in any case this is a handful of cases out of millions of women with implants. That would pretty much be the definition of hypoallergenic! As manufacturing standards have improved over the past 15-20 years, these types of cases should be even more rare now. Silicone is probably the most "biocompatible" synthetic material known, meaning that it generates very little response and so the body accepts it very well. Of all of the substances we are exposed to in a typical day, silicone is among the most benign.

No medical device in the history of Medicine has been as extensively studied as Breast Implants. Preposterously, breast implant were more extensively scrutinized than heart valves, pace makers, defibrillators, artificial joints etc.
After thousands of studies, these studies have demonstrated that implants do NOT cause immune disease, cancer or allergic reactions.I have never met a patient with an allergic reaction to breast implants in the many patients I placed implants in.
Dr. P. Aldea

Breast implants are non-reactive.  There should be no allregic reaction to them as shown in multiples studies over the past 15 years to get approval by the FDA.