Yes, you can do both, but I would suggest you will find some great information on ThermiTight, in the two articles I published last year. Both in the Journal of Drugs and Dermatology, which are all about ThermiTight.I would suggest you do the ThermiTight first, which is all about reducing fat from the jowls and underchin, at the same time tightening skin.For the second step, rather than Lutronic's CO2, I would check out Lutronic's newer INFINI, intense focused RF treatments. In hour hands at Key Laser the newer INFINI treatments are giving results like Ultherapy and CO2 combined together, with a healing time measured in days not the weeks to months as seen with CO2.