Dear foreveryoung908,There are many causes of gynecomastiaboth endogenous and exogenous. There isno medical study documenting artificial sweeteners like Splenda or Aspartamecausing gynecomastia. If you do havegynecomastia I would look for primary and secondary causes and if these areruled out then seek radio frequency assisted lipo contouring and reduction asthis can be performed with minimal scarring.I hope this information is of someassistance and best of luck.To find out more, please visit thelink below.R. Stephen Mulholland, M.D.Certified Plastic SurgeonYorkville, Toronto