The safety relays on the products used and who is injecting them. If you go to Tijuana, first you need go to a Board Certified Plastic Surgeon or Dermatologist, check your physician has extensive experience injecting fillers, also ask for before and after photos of his/her work, so you can have an idea about the results. Very important is to check what product the doctor will suggest for your case, the possible duration of the results, the amount needed for your case, the possible side effects and contraindications. Most of the fillers used in the U.S. are available in Mexico, like Juvederm, Restylane, Belotero, Radiesse, etc, and those are imported in Mexico and they are approved by the FDA in the U.S. There are some fillers available in Mexico that are not available in the U.S. yet like Juvederm Volbella or Juvederm Volift, but them are approved in Europe.