Can Botox injected too deeply seep into the Zygomaticus muscle?

Hi Anna.  While it's certainly possible that Botox injected to the eye area could have migrated downward into the Zygomaticus, the duration of the Botox would not be causing the concerns you have currently.  Botox won't last more than about 6 months at most which means if you did have any droop in the area (which would more likely show up around the lip) it would be worn off by now.  It sounds like you may need some dermal fillers to give you back cheek volume that has been lost. 

Botox can be injected into any muscle, but there are certain muscles we stay away from because the results will actually be worse. We typically do not inject directly into the zygomaticus muscle, but it is possible that the muscle was inadvertently injected or the Botox migrated into the muscle. In any case, Botox effects only last 3-4 months and things should go back to normal once it wears off. If you are still having issues then you need to follow up with an experienced physician for an in-person examination. Best wishes. 

Botox results last up to 3-4 months and can be softened with venus legacy and thermage treatments. I recommend getting a formal evaluation with a cosmetic dermatologist. Best, Dr. Emer

Sometimes botox can be injected to close to the zygomaticus and affect a full smile. It should last no longer than 4 months and will not cause permanent changes to the muscle or motor memory function. It is possible that during the past 14 months natural aging and/or weight changes can affect how you normally look rather than the botox. I notice this particularly in someone's 30s where facial aging occurs the most rapidly and becomes more noticeable as temporary treatments such as botox or fillers wear off. Hope this helps!
Johnson C. Lee, MD
Board-Certified Plastic Surgeon

1.Botox in the zygomaticus major muscle will cause cheeks to drop and affect the smile also
2. Effect of botox will last 4 months
3.Not unusual to lose cheek projection with age/lean body . Very easily and effectively treated with dermal filler
4. Cheeks are the foundation of the face. A good treatment will result in indirect improvement of
     -nasolabial folds
    - tear troughs
   - improvement of jowls
   - slight elevation of lips

Botox really should only last 3-4 months. It's possible, but very unlikely, that a nerve was irritated or something else happened at the time of injection. I would recommend that you head in to an injector that you trust and have him or her take a really good look at your face and how you move your muscles. We can then see what is going on and have recommendations. Also, remember that since it was 14 months ago, there are likely other aging processes involved here too-- like fat pad separation or bone loss. My guess would be that those are more likely the culprit, but we won't know until we get a look at ya. There are some GREAT providers in your area, so don't be afraid of going in and asking questions!
Best,
@DrKatNP.trilogy

Hello Anna B.,
Thank you for your question. I am sorry about your experience. Depending on where in the face you were injected with Botox if it was in close proximity to the zygomaticus major it is possible to affect the function of that muscle and cause cheek droop and even affect your smile. However since it has been 14 months since the injection it is not likely for that to be still active since Botox lasts for 4 months or 6 months at the longest. I recommend you see a plastic surgeon to better evaluate your face. If  you need improvement in your cheeks a dermal filler can be a good option. 
I hope this helps and wish you all the best.
Inzhili Kitto, M.D.
Plastic Surgeon
Instagram: @Dr_Kitto

Yes  if you noticed a drop in your cheek then the Zygomaticus muscle very likely was injected with Botox.  Whether the volume loss is related would require evaluation by a plastic surgeon or someone who specializes in facial reconstruction.  I would advice such a consultation.  Good luck.

If you had a cheek drop that means your zygomaticus muscle was in fact injected with botox. You need to be evaluated by a plastic surgeon or dermatologist to determine what should be done. Good luck from New York City