I'm going on holidays for 2 weeks, and plan on drinking and laying out in the sun. Will this affect accutane?
Doctor Answers 3
Because isotretinoin is metabolized by the liver, taking any other medications also metabolized by the liver (like tylenol, motrin) will stress/damage this organ. Alcohol plus isotretinoin will increase the chance your liver enzymes will be elevated. Because many dermatologists who write isotretinoin check labs every month, it is possible the enzymes would be elevated after any drinking binge. This elevation may prompt discontinuation of isotretinoin.
In summary, it would be advisable to avoid prolonged drinking of alcoholic beverages and prolonged sun exposure during treatment with isotretinoin.