Can thick alar skin be treated by non invasive face based RF treatment/ultrasonic cavitation/nano-surgery used for face?

Can it be treated by topical aminophylline+caffeine +yohimbine in sub cutaneous carrier(dmso) ? Can it be treated by lecithin + deoxycholate in sub cutaneous carrier(dmso) ? Many studies say that these topical approaches work on abdomen girth & thighs . No surgeon is ready to innovate on it. Curiously alar skin thickness can make a huge difference between level of perfection in nasal beauty e.g difference between the beauty of Tom cruise & Robert De Niro .