This is one of my favorite thing to do! And to answer your question, I am pretty sure your concerns can be addressed. But it might involve more than one therapy. Fillers could potentially soften your Cupid's bow area and threading and fillers could help subtly redirect your modiolus (corner of your mouth) upward or at least make them more horizontal. It is very important, in my opinion, to see a Board Certified Plastic Surgeon who has experience with both cosmetic surgery, and with minimally invasive procedures (fillers, threads, etc...) to help you achieve your goals. It is only with a solid knowledge of anatomy, tissue dynamics as well as aesthetics, that will give you the best chance of the look you're going for.I hope this helps!