Studies demonstrate the elevated hormone levels in women who have general anesthesia can increase the risk of blood clot and/or pulmonary embolus. While this is a very rare complication, we can not tell you that you should not stop the therapy.Mirena is an IUD and it works by manipulating hormone levels (even though you don't have to take a pill). It's really a great device and a lot of women are happy with it. So, the hard answer is "NO", you shouldn't have it in place at the time of surgery. While the risk is very low, the philosophical issue is that the down side of being wrong is simply too far down.Speak to your doctor - both the gynecologist and the plastic surgeon before you make any decisions.Good Luck!