I have hybrid permanent upper denture that are screwed in. I am concerned about cleaning, advice?

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There is now a better alternative to screws.   The same company that makes the Snap in Denture attatchments for removable snap in dentures now has created a screw free alternative that only can be removed by dentist.  It is a cleaner and easier to manage fixed denture with no screws or screw holes makeing in ideal .  It can be easily removes by hydraulics in the dental office.
Personally, I prefer the snap in denture thart is far easier to clean but  the same company is now making a fixed snap.
Good news for all on four or six denture patients.

Is all on four a good idea?  If one implant fails the case fails, additional implants decrease risk but increase cost and complexity.
This new F-Tx system reduces complexity.
Ira L Shapira DDS, D,ABDSM, D,AAPM, FICCMO
Chair, Alliance of TMD Organizations
Diplomat, American Academy of Pain Management
Diplomat, American Board of Dental Sleep Medicine
Regent & Fellow, International College of CranioMandibular Orthopedics
Board Eligible, American Academy of CranioFacial Pain
Dental Section Editor, Sleep & Health Journal
Member, American Equilibration Society
Member, Academy of Applied Myofunctional Sciences

We recommend that our patients use WaterPik as well as different types of flossing materials that could be inserted underneath the prosthesis. Although there are other hygiene aids that can be used, keep in mind that your restorative dentist can remove the prosthesis and have it cleaned professionally in his or her office. 

You can easily clean this with either superfloss or  a waterpik, go to your routine visits to get this checked and have x-rays just to make sure everything is fine.