Yes, epinephrine can cause temporary tachycardia, palpitations, shakiness, or a flushed feeling, similar to what some people notice after dental anesthetic. In liposuction, however, epinephrine is usually mixed into tumescent fluid in a very dilute concentration and is placed throughout the fatty layer. Its purpose is to reduce bleeding and slow absorption of the local anesthetic. Because it is dilute and absorbed gradually, most patients do not get the same sudden rush they may feel after a dental injection, but it can still happen, especially in people who are sensitive to epinephrine, anxious, dehydrated, taking stimulants, or who have thyroid disease, rhythm problems, or certain medications. Your surgeon and anesthesia team should know if you have a history of palpitations, SVT, atrial fibrillation, high blood pressure, panic attacks, or bad reactions to dental numbing medicine. During surgery your heart rate and blood pressure should be monitored, and dosing should be adjusted to your medical history and the planned amount of liposuction.