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Minoxidil doesn't work for beard growth for everyone, but if you have psoriasis and plan to use it, you may want to use it under monitoring of a dermatologist. It's unlikely to flare as I often use minoxidil for treatment patients with psoriasis who have male pattern balding. But you are right. Anything that irritates could trigger a flare. Use cautiously under care of your doctor and if you flare you'll have a plan to stop the flare quickly.
You should be asking this question to your doctor. The management of psoriasis is a complex problem and should not be handled by an amateur.