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WORTH IT RATING* 47 ratings over 24 months
*Does not include "Not sure"

Hyaluronidase is an injectable enzyme solution that speeds the natural breakdown of hyaluronic acid. It is used to counteract the effects of hyaluronic acid-based fillers like Juvederm or Restylane—for those whose original dermal filler treatments did not turn out as they had envisioned. LEARN MORE ›

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Juvederm Made my Eyes Ugly, Hyaluronidase Gave my Confidence Back!! - Washington, DC

My doctor offer Juvederm Plus to help my tired looking eyes. He injectted 1/2 a vile just under each tear duct. I got a black eye that lasted 4 weeks. Immediate swelling which he said was normal. At 1.5 months I went out with friends and reviewed the photos of the "new me" in horror. I... READ MORE

Saggy Loose Lower Eyelids from Juvederm then Hyaluronidase

I had too much Juvederm injected into the wrong place. It led to chronic bags, poor contour and a very tired, old look. A few years ago I had Restylane in the same place with no issues. It looked great and lasted a long time. Hyaluronidase was recommend to dissolve the Juvederm... READ MORE

27 year old Hyaluronidase ruined my face

I had fillers in march this year , however the dr is inexperienced and it looked really ugly , my upper cheeks areas, i had 2 cc of fillers , one in each cheek,,, so i decided to dissolve the filler , the dr used too much of hyaluronidase 350 units, which caused me to loose the fat in the upper... READ MORE

Hyaluronidase is Safe Don't Suffer with Bad Filler!

I'm writing the review because I too was unsure of hyaluronidase and confused about the reviews. I'm here to reassure you that , it does work. I had juvaderm ultra plus in my nasolabial folds and the plastic surgeon inh bred very high on the corners of my nose causing a buttress , enhancing my... READ MORE

Very Helpful - Montreal, QC


Hyalanex to dissolve undesireable tear trough filler

Sharing my latest photo after my last round of Hyalanex with Dr: Mabrie and in so thrilled he has artfully and precisely removed nearly all the Voluma and Volbello I had placed by another injector. I didn't know where my previous injector placed the product so Dr. Mabrie has been so patient and... READ MORE

33 y/o fixed a Filler/ Overdissolved problem with more filler. Finally happy!

I had juvederm injected into the nasolabial folds and lower cheek. This was a total mistake for me because it just made the bottom of my face look fat (versus lifting my cheeks and looking more angular which is what I wanted). I had it dissolved with Hydralonidase and it left my skin permanently... READ MORE

I Recommend Her Highly - New York, NY

Dr Green was just wonderful. We had such a headache with my previous practitioner not wanting to send the files and promising to do so, and it really held Dr Green up, so instead of being annoyed, SHE called them herself and got the owner on the phone by pretending to be a news outlet wanting... READ MORE

Crepy Skin After Vitrase - Lexington, KY

For those who are considering dissolving filler please understand that you are playing Russian Roulette with your face. Many people have had success with these products but using them has ruined my life. I was looking for some fullness in my face as I am in my early 50's and thin. I was... READ MORE

Hyaluronidase Dissolved Natural Tissue - Will It Regenerate?

Hi There, I had voluma dissolved with hyaluronidase from my cheekbones. There was only .2 of voluma in each cheek, and the doctor used half a unit of hyaluronidase to dissolve the filler a week later (I was desperately unhappy with the outcome and wanted to go back to how I was previously).... READ MORE

Filler Removal

I went to see Dr. Engler to dissolve a big amount of Juvederm Voluma that was injected on top and on the sides of my nose after several liquid rhinoplasties done over the course of two years with another doctor in Europe. The filler injected was just too much and I wanted it out of my face. Dr.... READ MORE

Ultrasound For Those of You Who Are Dealing with Filler Nightmares That Even Hyaluronidase Cannot Fix - New York, NY

Hello, I am sharing my experience with those who are dealing with a voluma/juvederm nightmare. Some of you may be too scared to get hyaluronidase, but an even more unfortunate number of you cannot dissolve the filler regardless of the amount of vitrase they have injected. I belong to the latter... READ MORE

Thank Goodness - Rancho Cucamonga, CA

I am no stranger to fillers. I have had good experiences with them, as well as complete life-altering nightmares. I recently decided to try filler again,and chose a Beverly Hills oculoplastic surgeon to inject my temples. He did (3 vials of Restylane total). While I was there, he convinced me to... READ MORE

Hyaluraonidase Save - Nashville, TN

After a bad outcome from under eye injections at another plastic surgeons office I went to see Lori Lankford at Dr. JJ Wendel's office. She explained that this injection would dissolve the unwanted filler. It was simple, easy and very effective. I went back to see her a few weeks later for... READ MORE

Hyaluronidase Works 5 Years After Dermal Filler Injection - London, TX

I had dermal fillers injected into my tear troughs and nasojugal lines when I was 27, I am now 32. I did it really because the nasojugal lines were asymmetrical. I have a slightly asymmetrical face to start off with. The initial treatment really worked. Flattened out my face, but a 3years later... READ MORE

Lynn Wojton is SIMPLY THE BEST! - New York, NY

Prior to seeing Lynn, I went to a new med spa recommended by a friend for the first time to just get a touch up of Botox on forehead and crows feet. Well sadly to say, the NP there convinced me hard to get Juvederm Voluma in my face/cheeks to add fullness. I have very high cheekbones and a... READ MORE

Removal of Juvederm Under Eyes - Illinois, IL

I've read several physicians on this site express that Hyaluronidase does not affect native hyaluronic acid, and a small percent of physicians that claim it does. Well, I would have to agree with the small percent. I had hyaluronidase administered in 3 separate sessions about a month apart under... READ MORE

Vitrase Dissolved Cheek Tissue - Portland, OR

I was overfilled with Restylane under the eyes and went to another doctor -- Dr. Dailey -- to have it removed with Vitrase. I specifically asked him if there was any chance that the Vitrase would permanently dissolve my own tissue. He was emphatic in saying no. So I agreed to have him inject... READ MORE

Hyaluronidase-works but Takes Times for HA to Regenerate - Orange County, CA

I've had hyaluronidase a few times over the past few years for bad filler (once under eye and twice for upper lip/smoker lines) and what I've found is that yes it absolutely leaves dents (I think it definitely eats away natural hyaluronic acid) BUT those dents do fill back in over time, in my... READ MORE

Hyaluronidase to Reverse Restylane Bags - AU

I had restalane under my eyes. I had it done previously just in the tear trough and loved it. This time I had a little more injected under the eye which in retrospect I probably did not need. My skin I found was extremely delicate. I swelled and bruised which is common with me and after weeks... READ MORE

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