Desoximetasone Cream or Fluocinonide Oil for Hair Loss?

This is difficult to answer without an evaluation. In our office, we've used injections of progesterone and PRP to great success. I recommend a consultation with a hair loss expert for best results. Best, Dr. Emer

First one needs to get the right diagnosis, then a decision can be made regarding treatment.  Both medications have been used to treat localized hair loss.  You need to be seen and evaluated by a dermatologist.

I'd need to see photos and ideally look up close to know what's going on. Stress causes hair loss all over rather than in a certain specific area like the sides. So this is not the primary cause of the hair loss. If it's alopecia areata, steroid injections are more effective than steroid lotions and creams. But desoximetasone and fluocinonide are both good starting options and can limit side effects. However, stronger topical steroids may be needed for alopecia areata. You'll want to speak to your dermatologist about side effects of stronger steroids, including skin thinning and pigmentation changes.  Petrolatum, lanolin and mineral oil are safe for most people, but yes rarely sensitivities are possible (especially lanolin).Avoiding relaxing will be helpful to ensure the newly growing hairs (if they grow) have the best chance of sporting back up. Hair improvements in alopecia areata should be obvious by 4-5 months. If not, one needs to revisit their dermatologist and determine if the diagnosis is correct or if other treatments are needed. Alopecia areata can certainly be challenging to treat, and it may be that other treatments are needed like steroid injections, anthralin, DPCP, or oral immunosuppressives. If the diagnosis is at all in question, a biopsy can be helpful.