Is applying 95% pure alcohol on scalp (twice daily, all life) safe for skin?

Minoxidil 5% liquid solution is made of 5% minoxidil + 95% pure alcohol. Solution must be applied twice every day, for the rest of user's life. Isn't that frequent and prolonged application of pure alcohol, eventually going to harm the skin/scalp where the solution is applied - cause an eczema or even cancer? And- which solution (liquid or foam) is less harmful for the skin & overall health? Liquid sol. contains 95% alcohol, foam sol. contains 30% alcohol + 50% propylene glycol + 15% water.

Doctor Answers 4

Minoxidil application to scalp

Studies have shown that Minoxidil 5% applied to scalp is safe for use twice a day.  The possibility of dry skin, eczema, dandruff or allergies to the medication have been reported. Should this occur, stop the medication and see a hair transplant specialist for other options.


Beverly Hills Hair Restoration Surgeon
5.0 out of 5 stars 28 reviews

Safe Hair Loss Solutions

Minoxidil is safe to apply twice a day. It does have some possible side effects, which can include skin irritation. I always recommend a consultation with a hair loss expert. There are great options for hair loss including: progesterone and PRP injections. Best, Dr. Emer

Jason Emer, MD
Los Angeles Dermatologic Surgeon
4.9 out of 5 stars 168 reviews

Is applying 95% pure alcohol on scalp (twice daily, all life) safe for skin?

Thanks for query. Minoxidil is by far safe to apply. It does cause some side effects like irritation, dandruff like lesions on the scalp. Liquid solution is better as it is more helpful. Cancer risks are very minute. Hope it helps.


All The Best

Ajaya Kashyap, MD
India Plastic Surgeon
4.9 out of 5 stars 132 reviews

Minoxidil solvents

Propylene Glycol is significantly more harmful than isopropyl alcohol to the body. 

Most of the 95% alcohol evaporates.  20 minutes exposure time to the scalp is needed for minoxidil to be absorbed.

Baubac Hayatdavoudi, MD
Beverly Hills Physician
5.0 out of 5 stars 41 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.