Ultherapy is a treatment that can get your attention if you're not prepared. In general, certain areas will be more tender than others and some patients (especially thinner) can feel the treatment more than others but if the patient is prepared appropriately, then the treatment can be very comfortable. In general, I wouldn't have the procedure done the first time without an anxiolytic (anxiety medication such as Xanax) and a pain pill. You'll find that this might be overkill for the treatment but you'll be relaxed and comfortable. If you go to have another Ultherapy treatment in a different area (which most people do because of the result), most people skip the pain pill and just go with the anxiolytic as that seems to do the trick. Being comfortable is important as it allows the ultherapist to do the best job possible. In our practice, we over treat by 30-50% to make sure our patients get a nice result and we charge the same as the local medspas but to treat our patients at this level, we do provide the anxiolytic and pain pill at time of scheduling. It also helps to have soothing music and a comfortable bed to sleep on when having it done as in our practice. Having this on a sterile exam table isn't as comfortable.