MRI scanning reports indicate no lipoma even when there are several very visible lipomas all my body.

They may be something else, so I would recommend a biopsy or excisional biopsy, and let's see what the pathologist thinks they are.Best Regards,Dr Michael Gartner

Thank you for sharing your question and I am sorry to hear of your diagnosis difficulties.  An MRI should be able to clearly differentiate a lipoma from surrounding fat.  If they are negative you may be suffering with lipodystrophy instead.  This can be treated with liposuction.  Hope this helps.

Despite common sense which would dictate that the very accurate MRI should see lipomas, I have had multiple patients who have palpable - even visible lipomas which an MRI has not identified, I believe this is because the lipomas are composed of fat which blends in with surrounding fatty tissue and are "invisible"  to imaging studies including ultrasound and mri. Other lipomas are easily demonstrated on mri and ultrasound. This may relate to how encapsulated they are. Imaging studies are complementary to physical exam and not the final arbiter. Consult a physician for further advice on how best to handle these masses. Good luck and take care.