Worst that can happen with Sclerotherapy to hands?

Hand veins are frequently used for IV medications but there are other options.  Hand rejuvenation focuses on three things: Thinning of the skin and loss of subcutaneous tissue which reveals veins and tendons, sun damage causing age spots and large veins themselves.  My first step is to address the skin using laser and/or IPL. Then, I recommend the use of Radiesse to restore the plumpness of the hand. Frequently, this hides the veins. If the veins are still an issue, sclerotherapy would be my next choice of treatment.

Hello,
I am not clear as why you would like to do sclerotherapy on your hands!!??
A photo would be helpful.
Instead, the most common approach would be to inject filler which is quite safe. that would add volume and I find it one of the best for hand rejuvenation.
Radiess is FDA Approved and last 12-18 months.
Other option would be fat transfer or better to say grafting. It is the best or only way to go grafting when the fat taken from your other area of body, APPROPRIATELY prepared and then inject it in the hands. Proper technique makes the fat grafting 80% successful while improper method, well 20-70% just matter of chance.
Good Luck -- Dr Ray