Thank you for your question. Vanquish Me destroys approximately 30% of the fat cells in a targeted area. This would be the same as if 30% of the fat cells were removed by liposuction. As for permanence of results, this is largely going to depend on your lifestyle choices. If you gain weight, fat cells in your body will get bigger and in some instances multiply. Further, visceral fat can increase which is a contributing cause to diabetes, hypertension, cardiovascular disease, stroke, and even death. Thus, once the procedure is performed, the end results are largely dependent on you adopting healthy lifestyle choices.I hope this was helpful - Dr. Moore.