Restylane Defyne vs Refyne for tear troughs, which would be longer lasting?

I have been injecting the tear trough regions for over three decades, since the early days with the use of the original Zyderm I collagen filler. Frankly,  would not opt for either Defyne or Refyne for use directly under the eyes. Each is intended for moderately severe wrinkles and folds, such as smile lines and marionette lines. Even plain Restylane is best injected diluted for use in this region, which is why many experienced injectors have switched to Restylane Silk. . In my Upper East Side Manhattan practice I prefer Belotero Balance for this purpose, since it possesses little to no tendency to give rise to the unwanted, bluish Tyndall Effect when it is injected superficially into the delicate tissues of this region. In my Israel satellite facility, where a far greater number of regulatory agency approved fillers are available, I typically choose Teosyal Redensity II.  Since fillers are subjected to little direct mechanical pressure (since the skin in this region is naturally so thin and distensible), most fillers can last an extremely long time when injected properly into this area. Results in my experience may last from about two years to as many as five plus. Look for a board certified aesthetic physician and make sure to ask to see his/her before and after photos before agreeing to proceed. Best of luck and welcome to the Big Apple.

Hi @Canadian_NewYorker! Restylane and Belotero both work great for the tear trough area! I recommend seeking treatments from expert injectors who have the skill and experience to precisely inject fillers into treatment areas and avoid risks and complications. Best of luck, Dr. Nima!

Restylane  is probably considered to be the gold standard treatment option for the tear troughs, but Refyne or Defyne is probably a reasonable option as well.  Good luck!

Thanks for this question. Restylane is a top choice for the tear trough. However, Refyne and Defyne will work. I don't believe there's any advantage in term of lasting results for the newer fillers. They all last about the same.Best wishes, Dr. ALDO 

I personally do not think they are worth the money.  Also they have a bit of the smooth filler characteristic, meaning they do not hold as precisely in the tissue as Restylane. I think this is just an effort by the manufacture to boost their bottom line.  There is a lot of hype on this filler. Don't get taken in. For the under eye circle, Restylane is still king in my opinion. Belotero is a "smooth" filler and too runny for the under eye area. Finding the right injector in New York City can be challenging.  I know because I see many New Yorker's who fly to see me in Beverly Hills for their under eye service.

Thank you for your inquiry.  Restylane Defyne and Refyne are typically used for correction of marionette and laugh lines. Restylane is usually used on tear trough area.  Best luck to you.

I do not believe there is any advantage to using Restylane Refyne/Defyne over Restylane-L for tear trough correction and so I stick with what has worked for me in this area. I inject Restylane into the tear troughs using a microcannula to minimize bruising and swelling. On a side note, I do prefer Restylane Refyne/Defyne over Restylane-L for laugh lines (nasolabial folds, marionette lines) because of the unique flexibility of these newer fillers which is useful in this area around the mouth.

Remember that any filler used in the under eye area is considered "off label."  That means that no filler has been developed specifically for this area.
In the opinion of most experienced injectors, Restylane or Belotero are the best products for the under eye.  Regardless of the filler that is used, the longevity of the filler in the under eye area is much longer compared to other parts of the face.  I have seen either product last 1.5 to 3 years in the under eye area.
More important than the type of filler used is having an experienced injector treat your under eye.  It is a very delicate area that takes good technique and experience.
Best of luck!

My personal preference for the under eye area is Restylane. Restylane Defyne and Restylane Refyne may also be ok for that area, however they are better suited for areas that have more movement such as the nasolabial folds or marionette lines. The skill of the injector and the technique are more important than the product. I prefer to inject with a cannula to reduce bruising in that very delicate area.

I think that either of these will be good for this area. I dont think there is any duration data to decide which one will last longer.
Defyne is designed for deeper volume loss areas so will probably be better for deeper tear troughs while Refyne is better for fine lines and wrinkles so probably will be best for mild tear trough deformities.