Many thanks for posting this interesting question.A seroma refers to the build up of a collection of wound fluid at the site of surgery (similar to the fluid in a blister). It is possible that this can occur after any operation, including facelifts.As a rule, the more extensive the facelift, and the more extensive the skin elevation, the higher the chance of a seroma (which is still a low chance overall). If surgical drains are used, any fluid comes out of them, but a seroma can still occur in some people after drain removal.If a seroma occurs, it is usually simple to deal with in the office, with a short painless needle aspiration (sucking out of the fluid). This might need to be done on more than one occasion.In terms of reducing the risks, in my view, the less you do, the better in the first few days after surgery. If you overdo it, then you might increase the risks of seroma development.I hope this answers your question.