Botox doesn't work anymore! Is there a way to make it work again?

Question

I have been getting botox, Dysport an Xeomin injections for years and now none of them work! I get a small effect but it does not last long. The procedure has been done by several different clinicians so I don't think it is the way it is done. I think I have built up a resistance. I love the effect when it works. Is there any new formulas or way to make it work again?

Manish H. Shah, MD, FACS · Answer

Hello hvar,Thanks for your question.With years of use of various neurotoxins, you have most likely developed significant antibodies.  In this situation, one thing that you can do is just use a larger does to try and offset the effect of the antibodies on removing the neurotoxin before it can even work to weaken the muscle.  Of note, it may be time for other treatments such as laser and surgery to manage some of the areas of wrinkles.See a specialist in facial rejuvenation, both Surgical and Nonsurgical, to be evaluated for the best option.Good luck,Dr. Shah

Jerome Edelstein, MD · Answer

You may want to consider having a more aggressive treatment, or explore other options if your body has built up a resistance to Botox. Fillers may help depending on the area you'd like to have treated.

Bryson G. Richards, MD · Answer

Thank you for your question. Please have your injector take good picture with you performing scowling or full smile motions. Take these pictures before and after. I am sure you will notice a difference. After time, the muscles can be so atrophied that the amount of improvement may seem less because the muscle isn't as strong to begin with before the treatment.I hope this helps.- Dr. Bryson Richards

Raffy Karamanoukian, MD, FACS · Answer

Its quite possible that you are resistant to the Botox injections. You may try to increase the dosage with a trained physician. Best, Dr. Karamanoukian Los Angeles Botox

Asif Pirani, MD, FRCS(C) · Answer

I have never seen this.  You may want to consider seeing a reputable physician with a lot of experience and stop shopping around.  You may find better results.

Botox doesn't work anymore! Is there a way to make it work again?

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Botox doesn't work anymore! Is there a way to make it work again?

Answers (7)

Answer: Botox specialist in Los Angeles

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Answer: Botox

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Everything you need to know about Botox

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