Hello - this is a good question and there are a few different options First lipomas can be one cystic type mas, or they may be "loculated " where they have more of a bubble wrap consistency and have many small lipomas in one larger area. Lipo can work well for them, but it has some problems. If the lipoma is loculated, then I find it harder to get a complete resolution. And- although I would say that lipo of a lipoma ( after evaluation to assure it is a lipoma and not anything else) works but in my opinion there is another option that I prefer. Lipomas can often be encased in a thicker outer layer, and have adhesions -areas scarred, or "stuck" to surrounding tissues. The mechanics of liposuction usually break up this denser tissue, and the fat inside is removed. However- adhesions usually come from healing, inflammation or trauma of some kind, and when we traumatize the adhesion to break it up, it can come back more dense and more firmly "stuck" to the tissue around it. It may not be a problem, but it can be, and can be more painful to treat. I prefer to use a diluted injectable fat disolving agent. Such as Kybella. The lipoma must be surperficial, easy to access, and the Kybella must be diluted so it does not create so much inflammation as to create adhesions, or worsen them. It allows me the finesse of a single spot, vs the larger areas involved in lipo. If a lipoma is more loculated, I find it easier to get all the internal smaller areas and create less tissue trauma and so less potential for adhesions. This is use of Kybella, is not the standard treatment, surgical excision is still the main way to address them in mainstream medicine. But the ability to do delicate work, and treat only the area of the lipoma can be useful. I mention it just as an option to consider. We can also use this dilute Kybella technique to etch out muscles and treat very small pockets of fat that would not warrent lipo. Hope that is helpful!