Does taking amitriptyline 10mg affect Botox?

Question

I.e reduces the lasting effects of Botox?

Kyle Coleman, MD · Answer

Botox duration should not be effected by amitriptyline.  Make sure to always inform your doctor of all your medications and medical history prior to any procedure.

Keith Denkler, MD · Answer

Low dose amitriptyline (10 mg) should not affect the results from Botox injection.Botox works locally and you will probably feel better when you look better.

Steven F. Weiner, MD · Answer

There is no interaction with this drug. In fact, Botox has been shown to improve depression which you probably are taking amitriptyline for.

Victor Chung, MD · Answer

Checking for drug interactions before starting any new medication or treatment is very important. In particular, Amitriptyline is known to have 267 major and 746 moderate drug interactions. Botox and Amitriptyline do not have any reported interactions. There is a remote possibility of dry mouth, blurred vision, or urinary issues based on the way each medicine works in your body. When injected properly, Botox will only work in the muscles where it is injected. If any new symptoms arise, it's always a good idea to contact your physician.I recommend that you consult with a trained professional for your first Botox injections. They can answer your questions and administer the Botox as safe as possible.

Matthew Elias, DO, FAAD · Answer

Thank you for your question.  Amitriptyline will not effect the duration of Botox, however there is a small chance the combo may increase anti-cholinergic like effects, i.e. dry mouth, blurry vision, etc.  For cosmetic dosing of Botox, I would not be concerned.  Regards, Dr. Matt Elias

Hratch Karamanoukian, MD, FACS · Answer

No, amitriptyline does not deletriously effect Botox metabolism.BestDr Karamanoukian#RealSelf100 Member

Does taking amitriptyline 10mg affect Botox?

Answers (6)

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