Which Retin-A Cream Is Best For Wrinkles----0.1% or 0.05%?

Question

I love Retin-A cream. So which is best for skin rejuvenation (wrinkles, tone), the strongest at 0.1% or 0.05%? I recently read that the strongest dose (0.1%) is ONLY for acne. I don't have pimple issues. Does that mean it won't also work for wrinkles? Darn...I've been using the highest dose for anti-aging. Do I return to the lower dose of 0.05% or stick with the 0.1% for maximum results. I believe the former studies were using the 0.05% for wrinkle research. Please advise. XOXO

Amy Miller, MD · Answer

The short answer to your question is to use the dose that is working for you.  If that is 0.1% then go for it! Many people cannot tolerate that high of a dose because it causes redness and peeling but if your skin has acclimated and you are not experiencing side effects it is absolutely fine.  Retin A, as a topical form of vitamin A, is great for your skin.  Make sure your are also protecting your skin with sunscreen and an antioxidant.
Keep up the good work!
Best,
Dr. Amy

Edwin Cortez, MD, FACS · Answer

If you have been tolerating the higher dose retinoid for your wrinkle treatment, I see no problem with continuing to use it.  It's obvious that your skin has become tolerant to the higher dose, o switching to a lower concentration would be unnecessary.

Charles M. Boyd, MD · Answer

Both Retin-A 0.05% and Retin-A 0.1% will be effective for helping with fine lines, wrinkles, and providing overall anti-aging benefits. The dose depends on how well you can tolerate the product. If you are not experiencing any of the typical side effects of Retin-A (redness, flaking, itchy, dry skin), then you can apply the 0.1% cream to see if that works better for you. Best of luck!

Which Retin-A Cream Is Best For Wrinkles----0.1% or 0.05%?

Answers (3)

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