Is there a possibility that the PRP will not be absorbed by the body?

Thanks for your question—and I completely understand the concern.

It’s not common, but occasionally after an O-Shot, patients may notice a small, firm area at the site of the injection, especially in the G-spot region. This is usually due to a localized collection of Platelet-Rich Plasma (PRP) or mild tissue swelling as part of the body’s healing response.

The good news is that this is typically temporary and resolves on its own within a few weeks as the PRP is absorbed and the tissue remodeling process continues.

If the area is:

Painful

Increasing in size

Red or warm to the touch

…then it should be evaluated, as these symptoms may suggest an infection or other rare complication. But in most cases, a firm bump after the O-Shot is benign and self-limiting.

We always encourage patients to reach out if they experience anything unusual so we can guide them properly. Feel free to share this with your friend—and we’re happy to provide a professional opinion if she’d like to be seen.

Warmly,
Dr. David Ghozland

Hi! I have never seen anyone reject or capsulize their own PRP. There is an calcium chloride activator added to the O shot and/or some offices add exosomes. I have never seen anyone have that type of reaction to an O shot or the calcium chloride. I would have your friend call the office and be seen for assessment so the provider can look further into this ball. Initially you will have some fluid that may look or feel somewhat engorged at the time of injection, but that should all flatten out within a couple of days at the most, if not way sooner. I hope that helps.

hello if the procedure is done with o shot which is prp , it doesn't leave any mass behind. but because of the application process to the tissue, there may be some bleeding which may be collected underneath the mucosa at the vagina g spot area. this is called hematoma and will be resolved in 3 weeks. best