Can the O shot work for a 75 year old woman?

Question

I never had trouble reaching the Big O, but lately it's hard. I was considering the O shot.

Mahmood Siddique, DO · Answer

Short answer: Probably not your best first step. The “O-shot” (PRP injected near the clitoris/anterior vaginal wall) has very limited, low-quality evidence for orgasm problems at any age. It isn’t FDA-approved for sexual function, results are inconsistent, and benefits&mdash;if any&mdash;tend to be modest and temporary. Risks are low but include pain, bruising, and infection.
Higher-yield things to try first
Local estrogen (vaginal cream/tablet/ring) or DHEA (prasterone) for dryness/atrophy that can blunt arousal and orgasm.
Pelvic-floor PT (over-tense muscles can block orgasm) and regular use of a strong vibrator/wand to increase arousal.
Medication review: SSRIs and some BP meds can delay orgasm&mdash;ask about switches or adding bupropion if appropriate.
Address health factors: diabetes control, neuropathy, cardiovascular fitness, sleep, alcohol.
If low desire is the main issue, discuss low-dose transdermal testosterone (off-label but guideline-supported in postmenopausal women with HSDD), plus sex therapy.
If you still want PRP
Manage expectations; there’s no solid RCT evidence it outperforms placebo.
Avoid if you have a bleeding/platelet disorder or are on strong anticoagulants.
Choose a clinician who uses true PRP (about 3–5× platelet concentration) and explains realistic outcomes and aftercare.
Bottom line: At 75, many women regain satisfying orgasms by treating vulvovaginal atrophy, optimizing stimulation, tuning meds, and working with pelvic-floor and sexual-health specialists. Try these first; consider the O-shot only as an optional, experimental add-on.

Can the O shot work for a 75 year old woman?

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Can the O shot work for a 75 year old woman?

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Recommended reading

Everything you need to know about O-Shot

Our mission is to create a world where every investment in modern beauty is Worth It.