O-Shot: Are there any side effects?

Immediate side effects, lasting up to several days, include 1) spotting, 2) swelling, and 3) hypersensitivity to sexual stimulation.Longer term effects include 1) increased moisture and 2) increased sensitivty

Great question—and it's important to know what to expect before undergoing any procedure.

The O-Shot® (Orgasm Shot) is generally very safe and well-tolerated, especially because it uses your own blood-derived PRP (Platelet-Rich Plasma). That said, here are a few potential side effects or things to be aware of:

Common (and typically mild) side effects:
Temporary swelling or mild soreness at the injection sites (usually resolves within 24–48 hours)

Mild spotting or discharge

Increased sensitivity (some patients notice heightened arousal for a few days)

Rare but possible:
Bruising (especially if you're prone to bruising or take blood-thinning medications)

Temporary urinary urgency or frequency

Localized itching or tingling sensation

Extremely rare:
Infection (very low risk due to sterile technique)

Allergic reaction – since it’s your own PRP, this is virtually nonexistent

What you won’t experience:
No downtime – most patients resume daily activities the same day

No general anesthesia or surgery – it’s a quick, in-office treatment under local numbing

The O-Shot is a minimally invasive procedure that requires no downtime and uses your body’s own platelet-rich plasma (PRP) to promote tissue regeneration, making it a safe and natural option for vaginal rejuvenation. While the treatment is generally well-tolerated, it’s important to discuss any potential risks with your provider before undergoing the procedure.