The answer to your question is that Botox only works well for certain areas of the face. For example, the wrinkles commonly referred to as "laugh lines", which extend downward from the side of the nose to the side of the mouth are not addressed with Botox. Because of the size of the crease in this area and the manner in which it forms, it is treated using dermal fillers such as Restylane, Juvederm or Perlane. The areas of the face where we commonly use Botox are as follows. In all cases, Botox works to address the issue of wrinkles in the particular area because it is able to relax the muscles that cause the wrinkles. The "11" lines, the vertical lines between the eyes. The horizontal forehead lines. The crow's feet on the outer sides of the eyes. The upper lip "smoker's lines".